Name
Age, Sex and Racial Differences in Long-Term Anti-Depressant Use in Primary Care: What should be done?
Description

This session will describe findings from a study of adult patients in 50 primary care practices who were prescribed antidepressant medication for more than two years. We will review variations in rates of antidepressant use by age, sex, and race. Small groups of participants will answer key questions regarding these differences and the implications for clinicians and primary care practices. The session will conclude with an exploration of future research questions relevant to long-term antidepressant use in primary care.

Speakers
Daniel Mullin PsyD, M.P.H., Professor, Individual - Daniel Mullin, Worcester,
Alison Karasz PhD, Professor, UMass Chan Medical School,
Sonal Singh MD, Associate Professor, UMass Chan Medical School,
Daniel Mullin
Co-Authors
Sarah Pearson, PsyD, Assistant Professor, UMass Chan Medical School, Worcester, MA
Content Level
All Audience
Tags
Pharmacology, Research and evaluation, Underserved populations such as LGBTQ+
Session Type
Concurrent
SIG or Committee
Research & Evaluation (REC)
Objective 1
Summarize current evidence supporting the effectiveness of antidepressant medication
Objective 2
Describe sex, race, and age based differences in long-term anti-depressant use
Objective 3
Describe the role of primary care teams in helping patients make informed decisions about long-term anti-depressant use
Content Reference 1

Cipriani, A., Furukawa, T. A., Salanti, G., Chaimani, A., Atkinson, L. Z., Ogawa, Y., Leucht, S., Ruhe, H. G., Turner, E. H., Higgins, J. P. T., Egger, M., Takeshima, N., Hayasaka, Y., Imai, H., Shinohara, K., Tajika, A., Ioannidis, J. P. A., and Geddes, J. R. (2018). Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis. The Lancet, 391(10128), 1357–1366. https://doi.org/10.1016/s0140-6736(17)32802-7

Content Reference 2

Linde, K., Kriston, L., Rücker, G., Jamil, S., Schumann, I., Meissner, K., Sigterman, K., and Schneider, A. (2015). Efficacy and Acceptability of Pharmacological Treatments for Depressive Disorders in Primary Care: Systematic Review and Network Meta-Analysis. The Annals of Family Medicine, 13(1), 69–79. https://doi.org/10.1370/afm.1687

Content Reference 3

Lewis, G., Marston, L., Duffy, L., Freemantle, N., Gilbody, S., Hunter, R., Kendrick, T., Kessler, D., Mangin, D., King, M., Lanham, P., Moore, M., Nazareth, I., Wiles, N., Bacon, F., Bird, M., Brabyn, S., Burns, A., Clarke, C. S., … Lewis, G. (2021). Maintenance or Discontinuation of Antidepressants in Primary Care. New England Journal of Medicine, 385(14), 1257–1267. https://doi.org/10.1056/nejmoa2106356

Content Reference 4

Luo, Y., Kataoka, Y., Ostinelli, E. G., Cipriani, A., and Furukawa, T. A. (2020). National Prescription Patterns of Antidepressants in the Treatment of Adults With Major Depression in the US Between 1996 and 2015: A Population Representative Survey Based Analysis. Frontiers in Psychiatry, 11, 35. https://doi.org/10.3389/fpsyt.2020.00035

Content Reference 5

Kelly, D., Graffi, J., Noonan, M., Green, P., McFarland, J., Hayes, P., and Glynn, L. (2021). Exploration of GP perspectives on deprescribing antidepressants: a qualitative study. BMJ Open, 11(4), e046054. https://doi.org/10.1136/bmjopen-2020-046054