The United States is increasingly diverse. Latinos comprise 19.1% of the U.S. population, and are expected to comprise well over 25% of the population by 2050. But a variety of health disparities threatens the future wellbeing of Latinos and, by extension, the nation. These disparities are driven by non-medical elements – the social determinants of health (SDoH) – in which Latino experience inequities. These SDoH issues, ranging from a lack of healthcare access to unaffordable housing to experiences of discrimination and a lack of representation, have been built into governmental laws, economic policies, school systems, neighborhoods, businesses, research, and healthcare. Reducing health disparities requires communicating advocacy and action for system changes to improve social and environmental factors and create more equitable living conditions for Latinos. That is the aim of the Salud America! program at the Institute for Health Promotion Research (IHPR), led Dr. Amelie G. Ramirez at UT Health San Antonio. Salud America! is a national, theory-based, Latino-focused communication network that creates and digitally shares culturally relevant news, stories, videos, and action tools for grassroots health policy and system changes that address SDoH and health inequities. From helping people create resolutions on racism as a public health crisis to providing a data visualization dashboard for people to quickly identify local health equity issues, Salud America! is communicating with its vast network of followers to share news, data, and action opportunities to promote system changes that can help set the stage for reduced health disparities across the U.S.