Patients, and their families, suffering from the impacts of chronic PTSD and a history of a mild traumatic brain injury (mTBI) commonly report frustration with their care. The UNC THRIVE Program was developed to address these barriers through an integrated, multidisciplinary model of care for Veterans and First Responders experiencing chronic PTSD and sequelae of mTBI. Selected participants attend a fully funded, three day comprehensive assessment, with all travel, lodging, and meals provided. Insurance status and military discharge characterization do not affect eligibility. Participants identified as having multiple treatable domains are invited to return for THRIVE’s three week Intensive Outpatient Program (IOP). The IOP is delivered in small cohorts of three to five participants and emphasizes individualized, evidence based treatment.