People with intellectual and developmental disabilities (I/DD) experience significant health disparities and fragmented access to care. Missouri recently launched one of the nation’s first statewide Developmental Disabilities Health Home programs, integrating medical, behavioral health, and social supports for approximately 11,000 individuals. This session highlights the innovative care model, early implementation lessons, and qualitative success stories from the program. Presenters will also discuss emerging evaluation strategies and future research priorities aimed at improving outcomes and reducing health disparities for people with I/DD. Attendees will gain practical insights for replicating integrated care models for complex populations.